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Calvin P H Vary Selected Research

Hereditary Hemorrhagic Telangiectasia

10/2020Overexpression of Activin Receptor-Like Kinase 1 in Endothelial Cells Suppresses Development of Arteriovenous Malformations in Mouse Models of Hereditary Hemorrhagic Telangiectasia.
2/2017Cancer incidence in patients with hereditary hemorrhagic telangiectasia.
1/2015BMP9 Crosstalk with the Hippo Pathway Regulates Endothelial Cell Matricellular and Chemokine Responses.
1/2014Improved survival outcomes in cancer patients with hereditary hemorrhagic telangiectasia.
11/2012BMP9 regulates endoglin-dependent chemokine responses in endothelial cells.
10/2009Endoglin plays distinct roles in vascular smooth muscle cell recruitment and regulation of arteriovenous identity during angiogenesis.
12/2007Novel biochemical pathways of endoglin in vascular cell physiology.
9/2006Endoglin structure and function: Determinants of endoglin phosphorylation by transforming growth factor-beta receptors.
8/2006Endoglin regulates cyclooxygenase-2 expression and activity.
8/2005Interaction and functional interplay between endoglin and ALK-1, two components of the endothelial transforming growth factor-beta receptor complex.
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Calvin P H Vary Research Topics

Disease

11Hereditary Hemorrhagic Telangiectasia
10/2020 - 06/2004
8Neoplasms (Cancer)
01/2019 - 12/2010
6Prostatic Neoplasms (Prostate Cancer)
01/2019 - 01/2008
5Vascular Remodeling
01/2018 - 12/2002
4Vascular Diseases (Vascular Disease)
01/2020 - 09/2006
3Inflammation (Inflammations)
01/2020 - 11/2012
3Neoplasm Metastasis (Metastasis)
10/2018 - 01/2011
3Carcinogenesis
08/2015 - 12/2010
2Mental Disorders (Mental Disorder)
12/2020 - 01/2020
2Schizophrenia (Dementia Praecox)
12/2020 - 01/2020
2Arteriovenous Malformations (Arteriovenous Malformation)
10/2020 - 06/2004
2Cardiovascular Diseases (Cardiovascular Disease)
01/2020 - 01/2019
2Inborn Genetic Diseases (Disease, Hereditary)
02/2017 - 01/2014
2Carcinoma (Carcinomatosis)
01/2016 - 12/2010
2Adenocarcinoma
05/2011 - 05/2008
2Vascular System Injuries
01/2005 - 12/2002
1Renal Cell Carcinoma (Grawitz Tumor)
11/2021
1Kidney Neoplasms (Kidney Cancer)
11/2021
1Non-alcoholic Fatty Liver Disease
12/2020
1Insulin Resistance
12/2020
1Obesity
12/2020
1Wounds and Injuries (Trauma)
10/2020
1Human Influenza (Influenza)
10/2020
1Bipolar Disorder (Manic Depressive Psychosis)
01/2020
1Melanoma (Melanoma, Malignant)
10/2018
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
04/2014
1Myeloid Leukemia (Leukemia, Myelocytic)
04/2014
1Ischemia
11/2012
1Hypoxia (Hypoxemia)
11/2012
1Pancreatic Neoplasms (Pancreatic Cancer)
05/2008
1Critical Illness (Critically Ill)
09/2006
1Neointima
01/2005
1Lipoma (Lipomata)
07/2004

Drug/Important Bio-Agent (IBA)

18EndoglinIBA
02/2017 - 12/2002
6Transforming Growth Factor beta (TGF-beta)IBA
06/2010 - 12/2002
4Proteins (Proteins, Gene)FDA Link
01/2019 - 07/2004
3CollagenIBA
10/2018 - 04/2014
3Transforming Growth Factor beta Receptors (TGF beta Receptors)IBA
03/2010 - 07/2004
224,25-oxidolanosterol (OLAN)IBA
12/2020 - 01/2020
2Risperidone (Risperdal Consta)FDA LinkGeneric
12/2020 - 01/2020
2Antipsychotic Agents (Antipsychotics)IBA
12/2020 - 01/2020
2Olanzapine (Zyprexa)FDA Link
12/2020 - 01/2020
2Biomarkers (Surrogate Marker)IBA
01/2019 - 02/2017
2EpitopesIBA
10/2018 - 01/2016
2Angiogenic ProteinsIBA
02/2017 - 01/2014
2Transforming Growth Factors (Transforming Growth Factor)IBA
01/2013 - 12/2010
1Oxygen (Dioxygen)IBA
11/2021
1Retinaldehyde (Retinal)IBA
10/2020
1Activin Receptors (Activin Receptor)IBA
10/2020
1Hemagglutinins (Hemagglutinin)IBA
10/2020
1LeptinIBA
01/2020
1Uncoupling Protein 1IBA
01/2020
1LipidsIBA
01/2020
1syncytinIBA
01/2019
1InterleukinsIBA
01/2019
1Annexin A5IBA
01/2019
1CytokinesIBA
01/2019
1Extracellular Matrix ProteinsIBA
10/2018
1CyclinsIBA
10/2018
1Annexin A2 (Annexin II)IBA
01/2018
1PlectinIBA
01/2018
1LigandsIBA
01/2016
1Monoclonal AntibodiesIBA
01/2016
1Fibroblast Growth Factor 1 (FGF-1)IBA
08/2015
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
08/2015
1Discoidin Domain Receptor 1IBA
04/2014
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
04/2014
1Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA
01/2013
1Activins (Activin)IBA
01/2013
1ChemokinesIBA
11/2012
1Complementary DNA (cDNA)IBA
11/2012
1Conditioned Culture MediaIBA
05/2011
1Insulin-Like Growth Factor Binding Protein 4IBA
05/2011
1Insulin-Like Growth Factor Binding ProteinsIBA
05/2011
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
12/2010
1Glycoproteins (Glycoprotein)IBA
03/2010
1Threonine (L-Threonine)FDA Link
03/2010
1Transforming Growth Factor-beta Type I ReceptorIBA
03/2010
1beta CateninIBA
05/2008
1GenisteinIBA
01/2008
1Testosterone (Sustanon)FDA Link
09/2006
1Estrogens (Estrogen)FDA Link
09/2006
1AndrogensIBA
09/2006
1Nitric Oxide Synthase (NO Synthase)IBA
08/2006
1PeriostinIBA
01/2005
1ZyxinIBA
07/2004
1AcidsIBA
07/2004
1Membrane Glycoproteins (Membrane Glycoprotein)IBA
12/2002
1Transcription Factors (Transcription Factor)IBA
12/2002

Therapy/Procedure

3Therapeutics
12/2020 - 01/2014
1Endarterectomy (Thromboendarterectomy)
01/2019